1074 Microseminoprotein-beta expression in different stages of prostate cancer
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چکیده
منابع مشابه
Microseminoprotein-Beta Expression in Different Stages of Prostate Cancer
Microseminoprotein-beta (MSMB, MSMB) is an abundant secretory protein contributed by the prostate, and is implicated as a prostate cancer (PC) biomarker based on observations of its lower expression in cancerous cells compared with benign prostate epithelium. However, as the current literature on MSMB is inconsistent, we assessed the expression of MSMB at the protein and mRNA levels in a compre...
متن کاملCorrection: Microseminoprotein-Beta Expression in Different Stages of Prostate Cancer
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متن کاملLevels of beta-microseminoprotein in blood and risk of prostate cancer in multiple populations.
BACKGROUND A common genetic variant (rs10993994) in the 5' region of the gene encoding β-microseminoprotein (MSP) is associated with circulating levels of MSP and prostate cancer risk. Whether MSP levels are predictive of prostate cancer risk has not been evaluated. METHODS We investigated the prospective relationship between circulating plasma levels of MSP and prostate cancer risk in a nest...
متن کاملThe rs10993994 Risk Allele for Prostate Cancer Results in Clinically Relevant Changes in Microseminoprotein-Beta Expression in Tissue and Urine
BACKGROUND Microseminoprotein-beta (MSMB) regulates apoptosis and using genome-wide association studies the rs10993994 single nucleotide polymorphism in the MSMB promoter has been linked to an increased risk of developing prostate cancer. The promoter location of the risk allele, and its ability to reduce promoter activity, suggested that the rs10993994 risk allele could result in lowered MSMB ...
متن کاملExpression and significance of S100P, CD147, and OCT4 in different prostate cancer tissue TNM stages.
The aim of this project was to investigate the expression and significance of S100P, CD147, and OCT4 in prostate cancer tissue at different TNM stages. We enrolled 54 patients with prostate cancer, 40 with benign prostatic hyperplasia, and 20 subjects with normal prostates. S100P, CD147, and OCT4 were detected by immunohistochemistry. The positive rate of S100P detection was 18.52% in prostate ...
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ژورنال
عنوان ژورنال: European Urology Supplements
سال: 2016
ISSN: 1569-9056
DOI: 10.1016/s1569-9056(16)61075-8